COVID-19
Laboratory
1copy™ BCR-ABL qPCR Kit

1copy™ BCR-ABL qPCR Kit is designed to evaluate the expression level of genes causing chronic myelogenous leukemia (CML), treat CML and monitor its recurrence.

Test Step Single Step
Limit of Detection(LoD) 4pg(~8 copies, >95%,CL)/ MR 4.77(MR value)
Target Gene 4 types of fusion mRNA(b3a2, b2a2, e1a2, e19a2)
Testing Time 2hr 25min
Sample Total RNA (Blood, Bone marrow)
Components
Components Container Color Volume
(100 tests)
Master mix Red 1000㎕
Primer Probe mix Brown
(Amber tube)		 100㎕
BCR-ABL1 Standard1
(1 X 106 copy / 2㎕)		 Green 50㎕
BCR-ABL1 Standard2
(1 X 105 copy / 2㎕)		 Green 50㎕
BCR-ABL1 Standard3
(1 X 103 copy / 2㎕)		 Green 50㎕
BCR-ABL1 Standard4
(1 X 102 copy / 2㎕)		 Green 50㎕
ABL1 Standard1
(1 X 106 copy / 2㎕)		 Blue 50㎕
ABL1 Standard2
(1 X 105 copy / 2㎕)		 Blue 50㎕
ABL1 Standard3
(1 X 104 copy / 2㎕)		 Blue 50㎕
Control1 Yellow 50㎕
Control2 Yellow 50㎕
DEPC Water Clear 1000㎕
Supporting Accurate Diagnosis

1copy™ BCR-ABL qPCR Kit shows a high level of sensitivity with a complete molecular response (CMR) of more than 0.00323% IS.

Category Period Level
Early Molecular Response 3 months BCR-ABL < 10%
Complete Cytogenetic Response 6 months BCR-ABL < 1%
Major Molecular Response 12 months BCR-ABL < 0.1%
Complete Molecular Response
(Deep Molecular Response or
Complete Molecular Response) 		After 12 months BCR-ABL < 0.0032%
Rapid and Convenient

Because 1copy™ BCR-ABL qPCR Kit can detect various target mRNAs in a single step, it is very quick and convenient to use.

1copy™ BCR-ABL qPCR Kit
(Single Step)		 Competitor
(2 steps)
Turn-around
Time		 2hr 25min 3hr 30min
Hands-on
time		 20min 1hr
Genotype Coverage

1copy™ BCR-ABL qPCR kit can detect Major type (p210 : e14a2, e13a2), Minor type (p190 : e1a2), Micro type (p230 : e19a2) of patient's genotype in a single test.